2022 Spatial Biology Access Program Award Recipients
Congratulations to the Spatial Biology Access Program Award Recipients
The Spatial Biology Access Program is designed to promote awareness of spatial biology at Seattle Children’s as well as the support and services provided by the Spatial Biology CoLab by funding new projects using these services. The Spatial Biology CoLab is an institutional resource to enable efficient and equitable access to state-of-the-art scientific equipment and expertise to advance collaborative, cutting-edge pediatric research.
Applications to the Spatial Biology Access Program were accepted from all Seattle Children’s Research Institute faculty and staff members for new projects, with projects that involved new collaborations between established investigators and early-stage investigators as well as between investigators across different Seattle Children’s research centers. The Shared Research Resources Steering Committee has given awards of up to $15K to seven exceptional collaborative research proposals, with funds covering the associated costs of using the Spatial Biology CoLab. Recipients of these awards are encouraged to present their findings at meetings focused on advancing collaborative science later this year.
2022 Recipients
Mechanistic assessment of HIV/SIV-related fatty liver disease (NAFLD) through GeoMx transcriptomic DSP evaluation of liver tissue from SIV-infected juvenile macaques and pediatric NAFLD patients.
Julie Park and Rithun Mukherjee
Defining tissue signatures of response and toxicity in pediatric cellular immunotherapy trials using spatial omics profiling and an accompanying analytics framework with broad applications.
Catalyzing an endogenous anticancer immune response with engineered Dual Costimulatory Receptor (DCR) T cell therapy.
Alexis Kaushansky and Joe Smith
Spatial profiling of Plasmodium falciparum infected erythrocytes in 3D human brain microvessels.
Spatial Transcriptomic Profiling to Elucidate Tissues and Pathways Affected in Hydrocephalus.
Cellular niche organization in bone marrow failure disorders underlies B cell aplasia.
James Bennett and Kelsey Loy
Evaluating Mosaic Architecture of Lymphatic Malformations Using Spatial Transcriptomics.
For more information, email the Spatial Biology CoLab team.