Psychophysiology and Behavioral Systems Lab

Led by Sara Jane Webb, PhD, the Psychophysiology and Behavioral Systems (PBS) Lab is dedicated to furthering research efforts into the etiology, course and treatment of developmental disabilities.

Through research into early development, neural processes, phenotyping and endophenotyping and clinical applications, PBS Labs aims to make a difference for individuals with developmental disabilities and their families.

PBS Labs counts on our families! Whether you are an individual with a developmental disability or not, you can join us in making a difference by participating in one of our research studies!

Explore Our Research

At PBS Labs we conduct research in a number of different areas specifically targeted to investigate the etiology, course, and treatment of developmental disabilities such as Autism Spectrum Disorder (ASD).

Behaviors and Executive Skills in T21 (BEST21)

The BUDDY Lab is conducting a study to understand the role of problem-solving in challenging behaviors for children with Down syndrome aged 6 to 14 years old. Children will complete 1 in-person visit that will include problem-solving games and a research EEG. Caregivers will complete some questionnaires about their child.

To participate, contact abcdownsyndrome@uw.edu.

Learn More About This Study

STRIPES: Study of Research Interests, Priorities, and Experiences

Our research team would like to learn more about the needs and priorities of individuals and families affected by genetic conditions. The information we learn may help us understand what research topics are most valuable to families and most likely to be helpful in the future. Participation involves filling out an online survey that asks your opinions and priorities for studies related to genetic conditions.

Join the Study

Autism Biomarkers Consortium for Clinical Trials (ABC-CT)

The Autism Biomarkers Consortium for Clinical Trials (ABC-CT) is a multicenter research study based at Yale that spans Duke University, Boston Children’s Hospital, the University of Washington/Seattle Children’s Research Institute and the Children’s Hospital of Los Angeles. The aim of the consortium is to develop reliable and objective measurements of social function and communication in autistic people.

To participate, contact Kleinhans lab.

BEAM Study

The Murray Lab is looking for autistic and non-autistic participants aged 18-30 for the Brain Engagement Attention and Modeling (BEAM) study exploring how the brain’s visual system processes motion.

Participants will complete online structured interviews and around 6 sessions of computer, behavioral, EEG and MRI experiments involving visual stimuli on UW campus. If you are interested in participating, please email rablab@uw.edu or call 206-221-2147.

L16hthouse

The L16HTHOUSE study is a Phase 2 clinical trial of arbaclofen in children with 16p11.2 deletion syndrome, a genetic condition associated with autism spectrum disorder (ASD) and other developmental challenges. The study aims to examine the safety, tolerability and efficacy of arbaclofen in improving speech, social function, cognition and motor skills in this population. Recruitment closed.