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FH9880: Multi-center phase II randomized controlled trial of naïve T cell depletion for prevention of chronic graft-versus-host disease in children and young adults

FH9880

Phase: II
Clinicaltrials.gov ID: NCT03779854

What is the goal of the study?

This is a multi-center, Phase II randomized controlled trial (RCT) comparing outcomes in pediatric and young adult patients receiving allogeneic hematopoietic cell transplantation (HCT) using either naïve T cell (TN)-depleted peripheral blood stem cell (PBSC) or unmanipulated T cell-replete bone marrow (BM). An initial feasibility phase will precede the RCT.

Who can participate in the study?

Everyone

Study Team:

PI (Study Doctor): Marie Bleakley
Study Team Member: Heather Persinger, hpersi@seattlechildrens.org