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Current Projects - Stein Lab - Seattle Children's Research

The Stein Lab is home to some of the latest ADHD research, working to improve diagnostics, access to care, and to develop more targeted treatments....

A Phase 2 Study of Blinatumomab in Combination with Chemotherapy for Infants with Newly Diagnosed Acute Lymphoblastic Leukemia with Randomization of KMT2A-Rearranged Patients to Addition of Venetoclax-STUDY00005483

To evaluate the safety and tolerability of venetoclax in addition to a standard chemotherapy backbone and two cycles of blinatumomab in infants...

A MASTER PHASE 1/2/3 PROTOCOL TO INVESTIGATE THE SAFETY, TOLERABILITY, AND IMMUNOGENICITY OF BIVALENT BNT162b2 RNA-BASED VACCINE CANDIDATE(S) IN HEALTHY CHILDREN -STUDY00003971

A multi-pronged, multi-phased study looking at the use of a bivalent RNA based COVID vaccine in children.

Repository and Registry for Immune-Mediated Diseases-PIROSTUDY14426B

To learn more about this study, please email the study team member listed below.

Resiliency in Families Affected by Congenital Heart Disease-STUDY00002036

To learn more about this study, please email the study team member listed below.

Collection of Biospecimens for Mucopolysaccharidosis Research-STUDY00002019

To learn more about this study, please email the study team member listed below.

PEPN2111: A Phase 1/2 Trial of CBL0137 (NSC# 825802, IND# 155843) in Patients with Relapsed or Refractory Solid Tumors including CNS Tumors and Lymphoma-STUDY00004362

CBL0137 is a novel small molecule inhibitor that is the first clinically developed drug in a new class of compounds termed ‘curaxins.’ It acts by...

Pediatric Immune Monitoring to Optimize Superior Allograft Outcomes in Transplantation Outcomes of KidneyCare in Renal Allografts-STUDY00003047

This is a prospective, multicenter observational study, with inbuilt real-time longitudinal sampling, and batched testing of novel measures....

NEONATAL ENTEROVIRUS AND HUMAN PARECHOVIRUS VIRAL SEPSIS: NATURAL HISTORY AND PREDICTORS OF MORBIDITY AND MORTALITY-STUDY00002450

Neonates presenting with clinical signs and laboratory data consistent with viral sepsis (who do not have a diagnosis of bacterial, HSV, CMV, or...

Pediatric Options for Migraine Relief: A Randomized, Double-Blind, Placebo-Controlled Study of Lasmiditan for Acute Treatment of Migraine: PIONEER-PEDS1-STUDY00002623

This study is being done to see how safe lasmiditan is and how well it will work to help people with migraines. This study will see how lasmiditan...