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Center for Immunity and Immunotherapies

For questions or inquiries, ciit@seattlechildrens.org
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Clinical Trial / Research Study

A Randomized Controlled Trial Using a Heuristic Tool to Improve Symptom Self-Management in Adolescents and Young Adults with Cancer

Adolescents and young adults with cancer experience multiple distressing symptoms during treatment. This study will test an intervention designed to improve...

Condition(s): Other Digestive Organ, Other Endocrine System, Other Female Genital, Other Hematopoietic, Other Male Genital, Other Respiratory and Intrathoracic Organs, Other Skin, Other Urinary, Ovary, Pancreas, Prostate, Rectum, Small Intestine, Soft Tissue, Stomach, Thyroid, Unknown Sites, Urinary Bladder, Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix, Colon, Corpus Uteri, Esophagus, Eye and Orbit, Hodgkin's Lymphoma, Ill-Defined Sites, Kaposi's Sarcoma, Kidney, Larynx, Leukemia, other, Lip, Oral Cavity and Pharynx, Liver, Lung, Lymphoid Leukemia, Melanoma, Skin, Multiple Myeloma, Mycosis Fungoides, Myeloid and Monocytic Leukemia, Non-Hodgkin's Lymphoma, Non-malignant Disease Clinicaltrials.gov ID: NCT05958316

Clinical Trial / Research Study

A Randomized Controlled Trial Using a Heuristic Tool to Improve Symptom Self-Management in Adolescents and Young Adults with Cancer

Adolescents and young adults with cancer experience multiple distressing symptoms during treatment. This study will test an intervention designed to improve...

Condition(s): Other Digestive Organ, Other Endocrine System, Other Female Genital, Other Hematopoietic, Other Male Genital, Other Respiratory and Intrathoracic Organs, Other Skin, Other Urinary, Ovary, Pancreas, Prostate, Rectum, Small Intestine, Soft Tissue, Stomach, Thyroid, Unknown Sites, Urinary Bladder, Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix, Colon, Corpus Uteri, Esophagus, Eye and Orbit, Hodgkin's Lymphoma, Ill-Defined Sites, Kaposi's Sarcoma, Kidney, Larynx, Leukemia, other, Lip, Oral Cavity and Pharynx, Liver, Lung, Lymphoid Leukemia, Melanoma, Skin, Multiple Myeloma, Mycosis Fungoides, Myeloid and Monocytic Leukemia, Non-Hodgkin's Lymphoma, Non-malignant Disease Clinicaltrials.gov ID: NCT05958316

Clinical Trial / Research Study

A Randomized Controlled Trial Using a Heuristic Tool to Improve Symptom Self-Management in Adolescents and Young Adults with Cancer

Adolescents and young adults with cancer experience multiple distressing symptoms during treatment. This study will test an intervention designed to improve...

Condition(s): Other Digestive Organ, Other Endocrine System, Other Female Genital, Other Hematopoietic, Other Male Genital, Other Respiratory and Intrathoracic Organs, Other Skin, Other Urinary, Ovary, Pancreas, Prostate, Rectum, Small Intestine, Soft Tissue, Stomach, Thyroid, Unknown Sites, Urinary Bladder, Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix, Colon, Corpus Uteri, Esophagus, Eye and Orbit, Hodgkin's Lymphoma, Ill-Defined Sites, Kaposi's Sarcoma, Kidney, Larynx, Leukemia, other, Lip, Oral Cavity and Pharynx, Liver, Lung, Lymphoid Leukemia, Melanoma, Skin, Multiple Myeloma, Mycosis Fungoides, Myeloid and Monocytic Leukemia, Non-Hodgkin's Lymphoma, Non-malignant Disease Clinicaltrials.gov ID: NCT05958316

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Glossary Term: 3-D imaging

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4800 Sand Point Way NE
Seattle, WA 98105

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Seattle Children's Hospital
PO Box 5371
Seattle, WA 98145-5005

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206-987-2000

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866-987-2000

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206-987-2226

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  • Loss of the ciliary kinase Nek8 causes left-right asymmetry defects.

    Manning DK, Sergeev M, van Heesbeen RG, Wong MD, Oh JH, Liu Y, Henkelman RM, Drummond I, Shah JV, Beier DR

    23274954 Journal of the American Society of Nephrology : JASN , 2013 Jan.: 24 (1 ) 100-12 PMCID: PMC3537214

  • Mutation mapping and identification by whole-genome sequencing.

    Leshchiner I, Alexa K, Kelsey P, Adzhubei I, Austin-Tse CA, Cooney JD, Anderson H, King MJ, Stottmann RW, Garnaas MK, Ha S, Drummond IA, Paw BH, North TE, Beier DR, Goessling W, Sunyaev SR

    22555591 Genome research , 2012 Aug.: 22 (8 ) 1541-8 PMCID: PMC3409267

  • Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo.

    Stottmann RW, Turbe-Doan A, Tran P, Kratz LE, Moran JL, Kelley RI, Beier DR

    21912524 PLoS genetics , 2011 Sept.: 7 (9 ) e1002224 PMCID: PMC3164675

  • The naive airway hyperresponsiveness of the A/J mouse is Kit-mediated.

    Cozzi E, Ackerman KG, Lundequist A, Drazen JM, Boyce JA, Beier DR

    21768379 Proceedings of the National Academy of Sciences of the United States of America , 2011 Aug 2: 108 (31 ) 12787-92 PMCID: PMC3150901

  • A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype.

    Dwyer ND, Manning DK, Moran JL, Mudbhary R, Fleming MS, Favero CB, Vock VM, O'Leary DD, Walsh CA, Beier DR

    21214893 Neural development , 2011 Jan 7: 6 3 PMCID: PMC3024922

  • Genome-wide identification of mouse congenital heart disease loci.

    Kamp A, Peterson MA, Svenson KL, Bjork BC, Hentges KE, Rajapaksha TW, Moran J, Justice MJ, Seidman JG, Seidman CE, Moskowitz IP, Beier DR

    20511334 Human molecular genetics , 2010 Aug 15: 19 (16 ) 3105-13 PMCID: PMC2908466

  • Prdm16 is required for normal palatogenesis in mice.

    Bjork BC, Turbe-Doan A, Prysak M, Herron BJ, Beier DR

    20007998 Human molecular genetics , 2010 Mar 1: 19 (5 ) 774-89 PMCID: PMC2816611

  • Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210.

    Smits P, Bolton AD, Funari V, Hong M, Boyden ED, Lu L, Manning DK, Dwyer ND, Moran JL, Prysak M, Merriman B, Nelson SF, Bonafé L, Superti-Furga A, Ikegawa S, Krakow D, Cohn DH, Kirchhausen T, Warman ML, Beier DR

    20089971 The New England journal of medicine , 2010 Jan 21: 362 (3 ) 206-16 PMCID: PMC3108191

  • PRDM16 controls a brown fat/skeletal muscle switch.

    Seale P, Bjork B, Yang W, Kajimura S, Chin S, Kuang S, Scimè A, Devarakonda S, Conroe HM, Erdjument-Bromage H, Tempst P, Rudnicki MA, Beier DR, Spiegelman BM

    18719582 Nature , 2008 Aug 21: 454 (7207 ) 961-7 PMCID: PMC2583329

  • THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia.

    Tran PV, Haycraft CJ, Besschetnova TY, Turbe-Doan A, Stottmann RW, Herron BJ, Chesebro AL, Qiu H, Scherz PJ, Shah JV, Yoder BK, Beier DR

    18327258 Nature genetics , 2008 April: 40 (4 ) 403-410 PMCID: PMC4817720

Research Center Contact Block

Center for Immunity and Immunotherapies

For questions or inquiries,
email: ciitadmin@seattlechildrens.org.

Physical Address

1900 Ninth Ave.
Seattle, WA 98101

Mailing Address

1900 Ninth Ave.
Seattle, WA 98101

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  • David J Rawlings, MD

    David J Rawlings, MD

    Director, Center for Immunity and Immunotherapies, Seattle Children’s Research Institute; Director, Program for Cell and Gene Therapy, Seattle Children’s Research Institute; Chief, Division of Immunology, Seattle Children's Hospital

  • First Name Middle Name Last Name, Honorific, PhD stuffs

    First Name Middle Name Last Name, Honorific, PhD stuffs

    Cardiology Attending, Echocardiography, Fetal Echocardiography

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David R Beier, PhD, MD

For questions or inquiries,
email: david.beier@seattlechildrens.org
telephone: 206-884-7358

Physical Address

Center for Developmental Biology and Regenerative Medicine
Jack McDonald Building 5th floor
1900 Ninth Ave.
Seattle, WA 98101

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  • Sean Gombart

    Sean Gombart

    Research Technician I

  • Scott Houghtaling, PhD School Location

    Scott Houghtaling, PhD School Location

    Research Lab Supervisor

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  • First Name Middle Name Last Name, Honorific, PhD stuffs

    First Name Middle Name Last Name, Honorific, PhD stuffs

    Acting Assistant Professor

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  • Elizabeth Vincent

    Elizabeth Vincent

    Postdoctoral Fellow

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David R Beier, PhD, MD School Location

David R Beier, PhD, MD School Location

Dr. David Beier completed his undergraduate education at Harvard University and obtained MD and PhD degrees from the Medical Scientist Training Program at the University of Washington. After completing an internship in pediatrics at Seattle Children’s Hospital, he returned to Harvard Medical School for post-doctoral training in Dr. Philip Leder’s lab, and to pursue clinical training in medical genetics. Dr. Beier joined the Harvard Medical School/Brigham and Women’s Hospital faculty in 1990 and became a professor there in 2005. He was also an Associate Member of the Broad Institute.

In 2013, he returned to Seattle to become Professor in Pediatrics at the University of Washington and Director of the Center for Developmental Biology and Regenerative Medicine at Seattle Children’s Research Institute. Dr. Beier has published over 150 research articles, and has served on numerous review panels for the NIH, March of Dimes, Genome Canada, and other organizations. He is an editor at PLoS Genetics and Mammalian Genome, and has served as a Secretariat member and President of the International Mammalian Genome Society. In 2017 Dr. Beier was awarded the Lillian Kaplan Prize for his research in polycystic kidney disease.

My research is consistently forward looking, with the aim of marrying enabling genomic technology with innovative strategies of genetic analysis. I have endeavored to make these approaches accessible, and have led a number of community initiatives.

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Phone Numbers

Appointment

206-987-2211

A provider referral is not required.

Addresses

Physical Address

4800 Sand Point Way NE
Seattle, WA 98105

Mailing Address

Seattle Children's Hospital
PO Box 5371
Seattle, WA 98145-5005

Hours

Business Hours

Sunday: 11:00a. m. - 8:00p. m.
Monday: 11:00a. m. - 10:30p. m.
Tuesday: 11:00a. m. - 10:30p. m.
Wednesday: 11:00a. m. - 10:30p. m.
Thursday: 11:00a. m. - 10:30p. m.
Friday: 11:00a. m. - 10:30p. m.
Saturday: 11:00a. m. - 8:00p. m.

Location Within Facility

Urgent Care can be found on the first floor opposite the emergency room.

Phone Numbers

Appointment

206-987-2211

A provider referral is not required.

Addresses

Physical Address

1500 116th Ave. NE
Bellevue, WA 98004

Mailing Address

Seattle Children's Bellevue Clinic and Surgery Center
PO Box 5371
Seattle, WA 98145-5005

Hours

Business Hours

Sunday: 11:00a. m. - 8:00p. m.
Monday: 4:00p. m. - 10:30p. m.
Tuesday: 4:00p. m. - 10:30p. m.
Wednesday: 4:00p. m. - 10:30p. m.
Thursday: 4:00p. m. - 10:30p. m.
Friday: 4:00p. m. - 10:30p. m.
Saturday: 11:00a. m. - 8:00p. m.

Phone Numbers

Appointment

206-987-2211

A provider referral is not required.

Addresses

Physical Address

1815 13th St.
Everett, WA 98201

Mailing Address

Seattle Children's North Clinic in Everett
PO Box 5371
Seattle, WA 98145-5005

Hours

Business Hours

Sunday: 11:00a. m. - 8:00p. m.
Monday: 4:00p. m. - 10:30p. m.
Tuesday: 4:00p. m. - 10:30p. m.
Wednesday: 4:00p. m. - 10:30p. m.
Thursday: 4:00p. m. - 10:30p. m.
Friday: 4:00p. m. - 10:30p. m.
Saturday: 11:00a. m. - 8:00p. m.

Phone Numbers

Appointment

206-987-2211

A provider referral is not required.

Addresses

Physical Address

34920 Enchanted Pkwy. S
Federal Way, WA 98003

Hours

Business Hours

Sunday: 11:00a. m. - 8:00p. m.
Monday: 4:00p. m. - 10:30p. m.
Tuesday: 4:00p. m. - 10:30p. m.
Wednesday: 4:00p. m. - 10:30p. m.
Thursday: 4:00p. m. - 10:30p. m.
Friday: 4:00p. m. - 10:30p. m.
Saturday: 11:00a. m. - 8:00p. m.

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Sports Medicine

Cora Collette Breuner, MD, MPH
Cora Collette Breuner, MD, MPH
Monique S Burton, MD
Monique S Burton, MD
Georgia McCabe Griffin, MD
Georgia McCabe Griffin, MD
Thomas M Jinguji, MD
Thomas M Jinguji, MD
Brian Joseph Krabak, MD, MBA
Brian Joseph Krabak, MD, MBA
John Hansell Lockhart, MD
John Hansell Lockhart, MD
Kyle Nagle, MD, MPH
Kyle Nagle, MD, MPH
Celeste Quitiquit, MD
Celeste Quitiquit, MD
Michael Saper, DO, FAOAO, FAAOS, ATC, CSCS
Michael Saper, DO, FAOAO, FAAOS, ATC, CSCS
Gregory A Schmale, MD
Gregory A Schmale, MD
Jeanette P Kotch, PA
Jeanette P Kotch, PA
Kari Dawn Robertson, PA-C, MHS
Kari Dawn Robertson, PA-C, MHS
Leslie Rodriguez, PA-C
Leslie Rodriguez, PA-C

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Teams

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Registered nurses

  • Mackenzie Boland, RN, BSN

  • Stacy Gallagher, RN, BSN

  • RaNette Schaff, RN, BSN, CPN

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Biofeedback therapists

  • Ria Abelon, MS, BCB

  • Seth Enos, ND, BCB

  • Margo Johnson, RN, PhD, BCN, BCB

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Registered dietitians

  • Amber D Brust, RDN, CD

  • Tran A Hang, MS, RDN, CD, CDE

  • Lauren Michelle Mozer, MPH, RDN, CD

  • Elena Ralph, MPH, RDN, CD

  • Lauren Rice, MPH, RDN, CD

  • Rebecca Rogers, MS, RDN, CD

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Social worker

  • Ilse Gagnaire, MSW

  • Andrew Gehl, MSW, LICSW

  • Alisa Koyama, MSW, LICSW

  • Erik Schlocker, LICSW

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8 Immune diseases treated at Seattle Children's 170 Genetic Immune Diseases
9 Engineered Cell & Gene Therapy Approved Treatments

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Director, Center for Developmental Biology and Regenerative Medicine

David R Beier, MD, PhD

David R Beier, MD, PhD

Dr. David Beier completed his undergraduate education at Harvard University and obtained MD and PhD degrees from the Medical Scientist Training Program at the University of Washington. After completing an internship in pediatrics at Seattle Children’s Hospital, he returned to Harvard Medical School for post-doctoral training in Dr. Philip Leder’s lab, and to pursue clinical training in medical genetics. Dr. Beier joined the Harvard Medical School/Brigham and Women’s Hospital faculty in 1990 and became a professor there in 2005. He was also an Associate Member of the Broad Institute.

In 2013, he returned to Seattle to become Professor in Pediatrics at the University of Washington and Director of the Center for Developmental Biology and Regenerative Medicine at Seattle Children’s Research Institute. Dr. Beier has published over 150 research articles, and has served on numerous review panels for the NIH, March of Dimes, Genome Canada, and other organizations. He is an editor at PLoS Genetics and Mammalian Genome, and has served as a Secretariat member and President of the International Mammalian Genome Society. In 2017 Dr. Beier was awarded the Lillian Kaplan Prize for his research in polycystic kidney disease.

My research is consistently forward looking, with the aim of marrying enabling genomic technology with innovative strategies of genetic analysis. I have endeavored to make these approaches accessible, and have led a number of community initiatives.

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Lab Team

Angela Marie Hernandez, MD Angela Marie Hernandez, MD
David R Beier, MD, PhD David R Beier, MD, PhD

Director, Center for Developmental Biology and Regenerative Medicine

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David R Beier, MD, PhD
David R Beier, MD, PhD Director, Center for Developmental Biology and Regenerative Medicine David Beier, MD, PhD, completed his undergraduate education at Harvard University and obtained MD and PhD degrees from the Medical Scientist Training Program at the University of Washington. Meet the Team

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Seattle Children’s complies with applicable federal and other civil rights laws and does not discriminate, exclude people or treat them differently based on race, color, religion (creed), sex, gender identity or expression, sexual orientation, national origin (ancestry), age, disability, or any other status protected by applicable federal, state or local law. Financial assistance for medically necessary services is based on family income and hospital resources and is provided to children under age 21 whose primary residence is in Washington, Alaska, Montana or Idaho.