Modern Blocks
Accordion Block
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Featured Content Cards Block (Modern)
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General Content Block
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iFrame Block
Lab Listing Block (Modern)
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Locations by Type PDF Block
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Locations Specialties PDF Block
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News Listing Block (Modern)
Publications Listing Block (Modern)
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Optimizing Genomic Methods for Mapping and Identification of Candidate Variants in ENU Mutagenesis Screens Using Inbred Mice.
Geister KA, Timms AE, Beier DR
29208648 G3 (Bethesda, Md.) , 2018 Feb 2: 8 (2 ) 401-409 PMCID: PMC5919724
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Estimating the selective effects of heterozygous protein-truncating variants from human exome data.
Cassa CA, Weghorn D, Balick DJ, Jordan DM, Nusinow D, Samocha KE, O'Donnell-Luria A, MacArthur DG, Daly MJ, Beier DR, Sunyaev SR
28369035 Nature genetics , 2017 May: 49 (5 ) 806-810 PMCID: PMC5618255
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C-Terminal Region Truncation of RELN Disrupts an Interaction with VLDLR, Causing Abnormal Development of the Cerebral Cortex and Hippocampus.
Ha S, Tripathi PP, Mihalas AB, Hevner RF, Beier DR
28123028 The Journal of neuroscience : the official journal of the Society for Neuroscience , 2017 Jan 25: 37 (4 ) 960-971 PMCID: PMC5296787
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High-resolution genetic localization of a modifying locus affecting disease severity in the juvenile cystic kidneys (jck) mouse model of polycystic kidney disease.
Beier DR
27114383 Mammalian genome : official journal of the International Mammalian Genome Society , 2016 June: 27 (5-6 ) 191-9
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Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.
Husson H, Moreno S, Smith LA, Smith MM, Russo RJ, Pitstick R, Sergeev M, Ledbetter SR, Bukanov NO, Lane M, Zhang K, Billot K, Carlson G, Shah J, Meijer L, Beier DR, Ibraghimov-Beskrovnaya O
27053712 Human molecular genetics , 2016 Apr 5
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Improvement of ENU Mutagenesis Efficiency Using Serial Injection and Mismatch Repair Deficiency Mice.
Gallego-Llamas J, Timms AE, Pitstick R, Peters J, Carlson GA, Beier DR
27441645 PloS one , 2016: 11 (7 ) e0159377 PMCID: PMC4956170
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Variant mapping and mutation discovery in inbred mice using next-generation sequencing.
Gallego-Llamas J, Timms AE, Geister KA, Lindsay A, Beier DR
26552429 BMC genomics , 2015 Nov 9: 16 913 PMCID: PMC4640199
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A forward genetic screen in mice identifies mutants with abnormal cortical patterning.
Ha S, Stottmann RW, Furley AJ, Beier DR
23968836 Cerebral cortex (New York, N.Y. : 1991) , 2015 Jan.: 25 (1 ) 167-79 PMCID: PMC4259276
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Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models.
Tran PV, Talbott GC, Turbe-Doan A, Jacobs DT, Schonfeld MP, Silva LM, Chatterjee A, Prysak M, Allard BA, Beier DR
24700869 Journal of the American Society of Nephrology : JASN , 2014 Oct.: 25 (10 ) 2201-12 PMCID: PMC4178433
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ENU mutagenesis in the mouse.
Stottmann R, Beier D
25723916 Current protocols in mouse biology , 2014 Jun 16: 4 (2 ) 25-35
Stat Row Block (Modern)
Team Listing Block (Modern)
David R Beier, MD, PhD
Director, Center for Developmental Biology and Regenerative Medicine
Team Member Block (Modern)