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Center for Immunity and Immunotherapies

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Clinical Trial / Research Study

A Randomized Controlled Trial Using a Heuristic Tool to Improve Symptom Self-Management in Adolescents and Young Adults with Cancer

Adolescents and young adults with cancer experience multiple distressing symptoms during treatment. This study will test an intervention designed to improve...

Condition(s): Other Digestive Organ, Other Endocrine System, Other Female Genital, Other Hematopoietic, Other Male Genital, Other Respiratory and Intrathoracic Organs, Other Skin, Other Urinary, Ovary, Pancreas, Prostate, Rectum, Small Intestine, Soft Tissue, Stomach, Thyroid, Unknown Sites, Urinary Bladder, Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix, Colon, Corpus Uteri, Esophagus, Eye and Orbit, Hodgkin's Lymphoma, Ill-Defined Sites, Kaposi's Sarcoma, Kidney, Larynx, Leukemia, other, Lip, Oral Cavity and Pharynx, Liver, Lung, Lymphoid Leukemia, Melanoma, Skin, Multiple Myeloma, Mycosis Fungoides, Myeloid and Monocytic Leukemia, Non-Hodgkin's Lymphoma, Non-malignant Disease Clinicaltrials.gov ID: NCT05958316

Clinical Trial / Research Study

A Randomized Controlled Trial Using a Heuristic Tool to Improve Symptom Self-Management in Adolescents and Young Adults with Cancer

Adolescents and young adults with cancer experience multiple distressing symptoms during treatment. This study will test an intervention designed to improve...

Condition(s): Other Digestive Organ, Other Endocrine System, Other Female Genital, Other Hematopoietic, Other Male Genital, Other Respiratory and Intrathoracic Organs, Other Skin, Other Urinary, Ovary, Pancreas, Prostate, Rectum, Small Intestine, Soft Tissue, Stomach, Thyroid, Unknown Sites, Urinary Bladder, Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix, Colon, Corpus Uteri, Esophagus, Eye and Orbit, Hodgkin's Lymphoma, Ill-Defined Sites, Kaposi's Sarcoma, Kidney, Larynx, Leukemia, other, Lip, Oral Cavity and Pharynx, Liver, Lung, Lymphoid Leukemia, Melanoma, Skin, Multiple Myeloma, Mycosis Fungoides, Myeloid and Monocytic Leukemia, Non-Hodgkin's Lymphoma, Non-malignant Disease Clinicaltrials.gov ID: NCT05958316

Clinical Trial / Research Study

A Randomized Controlled Trial Using a Heuristic Tool to Improve Symptom Self-Management in Adolescents and Young Adults with Cancer

Adolescents and young adults with cancer experience multiple distressing symptoms during treatment. This study will test an intervention designed to improve...

Condition(s): Other Digestive Organ, Other Endocrine System, Other Female Genital, Other Hematopoietic, Other Male Genital, Other Respiratory and Intrathoracic Organs, Other Skin, Other Urinary, Ovary, Pancreas, Prostate, Rectum, Small Intestine, Soft Tissue, Stomach, Thyroid, Unknown Sites, Urinary Bladder, Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix, Colon, Corpus Uteri, Esophagus, Eye and Orbit, Hodgkin's Lymphoma, Ill-Defined Sites, Kaposi's Sarcoma, Kidney, Larynx, Leukemia, other, Lip, Oral Cavity and Pharynx, Liver, Lung, Lymphoid Leukemia, Melanoma, Skin, Multiple Myeloma, Mycosis Fungoides, Myeloid and Monocytic Leukemia, Non-Hodgkin's Lymphoma, Non-malignant Disease Clinicaltrials.gov ID: NCT05958316

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Physical Address

4800 Sand Point Way NE
Seattle, WA 98105

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Mailing Address

Seattle Children's Hospital
PO Box 5371
Seattle, WA 98145-5005

Phone Numbers

Telephone

206-987-2000

Toll Free

866-987-2000

Interpreter Services

866-583-1527

TTY

206-987-0391

Driving Directions

206-987-2226

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  • Optimizing Genomic Methods for Mapping and Identification of Candidate Variants in ENU Mutagenesis Screens Using Inbred Mice.

    Geister KA, Timms AE, Beier DR

    29208648 G3 (Bethesda, Md.) , 2018 Feb 2: 8 (2 ) 401-409 PMCID: PMC5919724

  • Estimating the selective effects of heterozygous protein-truncating variants from human exome data.

    Cassa CA, Weghorn D, Balick DJ, Jordan DM, Nusinow D, Samocha KE, O'Donnell-Luria A, MacArthur DG, Daly MJ, Beier DR, Sunyaev SR

    28369035 Nature genetics , 2017 May: 49 (5 ) 806-810 PMCID: PMC5618255

  • C-Terminal Region Truncation of RELN Disrupts an Interaction with VLDLR, Causing Abnormal Development of the Cerebral Cortex and Hippocampus.

    Ha S, Tripathi PP, Mihalas AB, Hevner RF, Beier DR

    28123028 The Journal of neuroscience : the official journal of the Society for Neuroscience , 2017 Jan 25: 37 (4 ) 960-971 PMCID: PMC5296787

  • High-resolution genetic localization of a modifying locus affecting disease severity in the juvenile cystic kidneys (jck) mouse model of polycystic kidney disease.

    Beier DR

    27114383 Mammalian genome : official journal of the International Mammalian Genome Society , 2016 June: 27 (5-6 ) 191-9

  • Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis.

    Husson H, Moreno S, Smith LA, Smith MM, Russo RJ, Pitstick R, Sergeev M, Ledbetter SR, Bukanov NO, Lane M, Zhang K, Billot K, Carlson G, Shah J, Meijer L, Beier DR, Ibraghimov-Beskrovnaya O

    27053712 Human molecular genetics , 2016 Apr 5

  • Improvement of ENU Mutagenesis Efficiency Using Serial Injection and Mismatch Repair Deficiency Mice.

    Gallego-Llamas J, Timms AE, Pitstick R, Peters J, Carlson GA, Beier DR

    27441645 PloS one , 2016: 11 (7 ) e0159377 PMCID: PMC4956170

  • Variant mapping and mutation discovery in inbred mice using next-generation sequencing.

    Gallego-Llamas J, Timms AE, Geister KA, Lindsay A, Beier DR

    26552429 BMC genomics , 2015 Nov 9: 16 913 PMCID: PMC4640199

  • A forward genetic screen in mice identifies mutants with abnormal cortical patterning.

    Ha S, Stottmann RW, Furley AJ, Beier DR

    23968836 Cerebral cortex (New York, N.Y. : 1991) , 2015 Jan.: 25 (1 ) 167-79 PMCID: PMC4259276

  • Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models.

    Tran PV, Talbott GC, Turbe-Doan A, Jacobs DT, Schonfeld MP, Silva LM, Chatterjee A, Prysak M, Allard BA, Beier DR

    24700869 Journal of the American Society of Nephrology : JASN , 2014 Oct.: 25 (10 ) 2201-12 PMCID: PMC4178433

  • ENU mutagenesis in the mouse.

    Stottmann R, Beier D

    25723916 Current protocols in mouse biology , 2014 Jun 16: 4 (2 ) 25-35

Research Center Contact Block

Center for Immunity and Immunotherapies

For questions or inquiries,
email: ciitadmin@seattlechildrens.org.

Physical Address

1900 Ninth Ave.
Seattle, WA 98101

Mailing Address

1900 Ninth Ave.
Seattle, WA 98101

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  • David J Rawlings, MD

    David J Rawlings, MD

    Director, Center for Immunity and Immunotherapies, Seattle Children’s Research Institute; Director, Program for Cell and Gene Therapy, Seattle Children’s Research Institute; Chief, Division of Immunology, Seattle Children's Hospital

  • First Name Middle Name Last Name, Honorific, PhD stuffs

    First Name Middle Name Last Name, Honorific, PhD stuffs

    Cardiology Attending, Echocardiography, Fetal Echocardiography

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Research Lab Contact Block (Beier Lab)

David R Beier, PhD, MD

For questions or inquiries,
email: david.beier@seattlechildrens.org
telephone: 206-884-7358

Physical Address

Center for Developmental Biology and Regenerative Medicine
Jack McDonald Building 5th floor
1900 Ninth Ave.
Seattle, WA 98101

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  • Sean Gombart

    Sean Gombart

    Research Technician I

  • Scott Houghtaling, PhD School Location

    Scott Houghtaling, PhD School Location

    Research Lab Supervisor

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  • First Name Middle Name Last Name, Honorific, PhD stuffs

    First Name Middle Name Last Name, Honorific, PhD stuffs

    Acting Assistant Professor

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  • Elizabeth Vincent

    Elizabeth Vincent

    Postdoctoral Fellow

Research Lab Principal Investigators Block

David R Beier, PhD, MD School Location

David R Beier, PhD, MD School Location

Dr. David Beier completed his undergraduate education at Harvard University and obtained MD and PhD degrees from the Medical Scientist Training Program at the University of Washington. After completing an internship in pediatrics at Seattle Children’s Hospital, he returned to Harvard Medical School for post-doctoral training in Dr. Philip Leder’s lab, and to pursue clinical training in medical genetics. Dr. Beier joined the Harvard Medical School/Brigham and Women’s Hospital faculty in 1990 and became a professor there in 2005. He was also an Associate Member of the Broad Institute.

In 2013, he returned to Seattle to become Professor in Pediatrics at the University of Washington and Director of the Center for Developmental Biology and Regenerative Medicine at Seattle Children’s Research Institute. Dr. Beier has published over 150 research articles, and has served on numerous review panels for the NIH, March of Dimes, Genome Canada, and other organizations. He is an editor at PLoS Genetics and Mammalian Genome, and has served as a Secretariat member and President of the International Mammalian Genome Society. In 2017 Dr. Beier was awarded the Lillian Kaplan Prize for his research in polycystic kidney disease.

My research is consistently forward looking, with the aim of marrying enabling genomic technology with innovative strategies of genetic analysis. I have endeavored to make these approaches accessible, and have led a number of community initiatives.

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Phone Numbers

Appointment

206-987-2211

A provider referral is not required.

Addresses

Physical Address

4800 Sand Point Way NE
Seattle, WA 98105

Mailing Address

Seattle Children's Hospital
PO Box 5371
Seattle, WA 98145-5005

Hours

Business Hours

Sunday: 11:00a. m. - 8:00p. m.
Monday: 11:00a. m. - 10:30p. m.
Tuesday: 11:00a. m. - 10:30p. m.
Wednesday: 11:00a. m. - 10:30p. m.
Thursday: 11:00a. m. - 10:30p. m.
Friday: 11:00a. m. - 10:30p. m.
Saturday: 11:00a. m. - 8:00p. m.

Location Within Facility

Urgent Care can be found on the first floor opposite the emergency room.

Phone Numbers

Appointment

206-987-2211

A provider referral is not required.

Addresses

Physical Address

1500 116th Ave. NE
Bellevue, WA 98004

Mailing Address

Seattle Children's Bellevue Clinic and Surgery Center
PO Box 5371
Seattle, WA 98145-5005

Hours

Business Hours

Sunday: 11:00a. m. - 8:00p. m.
Monday: 4:00p. m. - 10:30p. m.
Tuesday: 4:00p. m. - 10:30p. m.
Wednesday: 4:00p. m. - 10:30p. m.
Thursday: 4:00p. m. - 10:30p. m.
Friday: 4:00p. m. - 10:30p. m.
Saturday: 11:00a. m. - 8:00p. m.

Phone Numbers

Appointment

206-987-2211

A provider referral is not required.

Addresses

Physical Address

1815 13th St.
Everett, WA 98201

Mailing Address

Seattle Children's North Clinic in Everett
PO Box 5371
Seattle, WA 98145-5005

Hours

Business Hours

Sunday: 11:00a. m. - 8:00p. m.
Monday: 4:00p. m. - 10:30p. m.
Tuesday: 4:00p. m. - 10:30p. m.
Wednesday: 4:00p. m. - 10:30p. m.
Thursday: 4:00p. m. - 10:30p. m.
Friday: 4:00p. m. - 10:30p. m.
Saturday: 11:00a. m. - 8:00p. m.

Phone Numbers

Appointment

206-987-2211

A provider referral is not required.

Addresses

Physical Address

34920 Enchanted Pkwy. S
Federal Way, WA 98003

Hours

Business Hours

Sunday: 11:00a. m. - 8:00p. m.
Monday: 4:00p. m. - 10:30p. m.
Tuesday: 4:00p. m. - 10:30p. m.
Wednesday: 4:00p. m. - 10:30p. m.
Thursday: 4:00p. m. - 10:30p. m.
Friday: 4:00p. m. - 10:30p. m.
Saturday: 11:00a. m. - 8:00p. m.

Specialty Team Gallery Block

Sports Medicine

Cora Collette Breuner, MD, MPH
Cora Collette Breuner, MD, MPH
Monique S Burton, MD
Monique S Burton, MD
Georgia McCabe Griffin, MD
Georgia McCabe Griffin, MD
Thomas M Jinguji, MD
Thomas M Jinguji, MD
Brian Joseph Krabak, MD, MBA
Brian Joseph Krabak, MD, MBA
John Hansell Lockhart, MD
John Hansell Lockhart, MD
Kyle Nagle, MD, MPH
Kyle Nagle, MD, MPH
Celeste Quitiquit, MD
Celeste Quitiquit, MD
Michael Saper, DO, FAOAO, FAAOS, ATC, CSCS
Michael Saper, DO, FAOAO, FAAOS, ATC, CSCS
Gregory A Schmale, MD
Gregory A Schmale, MD
Jeanette P Kotch, PA
Jeanette P Kotch, PA
Kari Dawn Robertson, PA-C, MHS
Kari Dawn Robertson, PA-C, MHS
Leslie Rodriguez, PA-C
Leslie Rodriguez, PA-C

Specialty Team Members Block

Teams

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Registered nurses

  • Mackenzie Boland, RN, BSN

  • Stacy Gallagher, RN, BSN

  • RaNette Schaff, RN, BSN, CPN

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Biofeedback therapists

  • Ria Abelon, MS, BCB

  • Seth Enos, ND, BCB

  • Margo Johnson, RN, PhD, BCN, BCB

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Registered dietitians

  • Amber D Brust, RDN, CD

  • Tran A Hang, MS, RDN, CD, CDE

  • Lauren Michelle Mozer, MPH, RDN, CD

  • Elena Ralph, MPH, RDN, CD

  • Lauren Rice, MPH, RDN, CD

  • Rebecca Rogers, MS, RDN, CD

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Social worker

  • Ilse Gagnaire, MSW

  • Andrew Gehl, MSW, LICSW

  • Alisa Koyama, MSW, LICSW

  • Erik Schlocker, LICSW

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8 Immune diseases treated at Seattle Children's 170 Genetic Immune Diseases
9 Engineered Cell & Gene Therapy Approved Treatments

Team Listing Block (Modern)

Director, Center for Developmental Biology and Regenerative Medicine

David R Beier, MD, PhD

David R Beier, MD, PhD

Dr. David Beier completed his undergraduate education at Harvard University and obtained MD and PhD degrees from the Medical Scientist Training Program at the University of Washington. After completing an internship in pediatrics at Seattle Children’s Hospital, he returned to Harvard Medical School for post-doctoral training in Dr. Philip Leder’s lab, and to pursue clinical training in medical genetics. Dr. Beier joined the Harvard Medical School/Brigham and Women’s Hospital faculty in 1990 and became a professor there in 2005. He was also an Associate Member of the Broad Institute.

In 2013, he returned to Seattle to become Professor in Pediatrics at the University of Washington and Director of the Center for Developmental Biology and Regenerative Medicine at Seattle Children’s Research Institute. Dr. Beier has published over 150 research articles, and has served on numerous review panels for the NIH, March of Dimes, Genome Canada, and other organizations. He is an editor at PLoS Genetics and Mammalian Genome, and has served as a Secretariat member and President of the International Mammalian Genome Society. In 2017 Dr. Beier was awarded the Lillian Kaplan Prize for his research in polycystic kidney disease.

My research is consistently forward looking, with the aim of marrying enabling genomic technology with innovative strategies of genetic analysis. I have endeavored to make these approaches accessible, and have led a number of community initiatives.

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Lab Team

Angela Marie Hernandez, MD Angela Marie Hernandez, MD
David R Beier, MD, PhD David R Beier, MD, PhD

Director, Center for Developmental Biology and Regenerative Medicine

Team Member Block (Modern)

David R Beier, MD, PhD
David R Beier, MD, PhD Director, Center for Developmental Biology and Regenerative Medicine David Beier, MD, PhD, completed his undergraduate education at Harvard University and obtained MD and PhD degrees from the Medical Scientist Training Program at the University of Washington. Meet the Team

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Regression Testing

Seattle Children’s complies with applicable federal and other civil rights laws and does not discriminate, exclude people or treat them differently based on race, color, religion (creed), sex, gender identity or expression, sexual orientation, national origin (ancestry), age, disability, or any other status protected by applicable federal, state or local law. Financial assistance for medically necessary services is based on family income and hospital resources and is provided to children under age 21 whose primary residence is in Washington, Alaska, Montana or Idaho.